2-Fluoro-4-(trifluoroMethyl)phenylboronic Acid, identified by CAS 503309-11-3, is a fluorinated aryl boronic acid used primarily as a building block in organic synthesis and pharmaceutical research. Its molecule combines a boronic acid group with both fluoro and trifluoromethyl substituents, providing a useful platform for Suzuki–Miyaura cross-coupling and related transformations. At Maison Chemical, we supply this compound for customers who need a defined research or manufacturing intermediate, subject to product specification, batch availability, and applicable shipping requirements.
The commonly assigned molecular formula is C7H5BF4O2, with a calculated molecular weight of approximately 207.92 g/mol. Because commercial handling requirements can vary by grade, quantity, and intended use, buyers should confirm the current certificate of analysis, appearance, assay, water content, and storage instructions before ordering. This page explains the compound’s identity, functions, application scenarios, specification considerations, and how to evaluate a suitable supplier.
2-Fluoro-4-(trifluoroMethyl)phenylboronic Acid is an organoboron compound containing an aryl boronic acid functionality. The boronic acid group can participate in palladium-catalyzed carbon–carbon bond formation, especially when reacted with suitable aryl or heteroaryl halides under Suzuki–Miyaura coupling conditions. The fluoro and trifluoromethyl groups modify the electronic and lipophilic characteristics of the aromatic ring, which can be valuable during medicinal chemistry design and intermediate development.
CAS 503309-11-3 is the registry identifier used to distinguish this specific chemical substance from related fluorinated boronic acids. Buyers should not rely only on a similar product name because positional isomers can have different reactivity, analytical profiles, and suitability for a synthesis route. We recommend confirming the CAS number, structural name, molecular formula, and analytical documentation together during technical purchasing.
The main function of this compound is to serve as a boronic acid coupling partner. In a typical Suzuki–Miyaura reaction, the aryl boronic acid reacts with an aryl or heteroaryl halide to form a biaryl connection. This reaction can help medicinal and process chemists assemble complex aromatic structures from modular starting materials.
The fluoro substituent and trifluoromethyl substituent are already incorporated into the aromatic building block. This can reduce the number of synthetic steps required to introduce those groups separately, although the final route must still be evaluated for reaction compatibility and yield. Their electronic effects may influence downstream reaction behavior, purification, and the properties of the final target molecule.
Customers may use the compound in early-stage discovery, route scouting, analytical reference preparation, or process development. Its actual value depends on the target structure, reaction conditions, scale, and quality requirements. We therefore treat technical fit and documentation as equally important as nominal availability.
This compound is most relevant to pharmaceutical and fine chemical synthesis where a substituted biaryl or heteroaryl structure is required. It may be evaluated in the preparation of research compounds, advanced intermediates, and other fluorinated organic molecules. The suitability of CAS 503309-11-3 should be demonstrated through the customer’s own reaction screening or validated process data rather than assumed from the name alone.
A product specification should include more than the product name and CAS number. We recommend reviewing the molecular formula, molecular weight, assay method, chromatographic purity, water content, residual solvents, elemental impurities where relevant, and the appearance of the supplied material. The exact limits should be agreed according to the application, since research use and regulated manufacturing may require different documentation packages.
| Specification item | Information to confirm |
|---|---|
| Identity | CAS 503309-11-3, chemical name, structure, and analytical identification |
| Molecular information | C7H5BF4O2; approximately 207.92 g/mol |
| Purity | Assay or HPLC/GC purity requirement agreed before purchase |
| Physical form | Current appearance, color description, and packaging format |
| Stability and storage | Supplier-recommended temperature, moisture protection, and retest guidance |
| Documentation | Certificate of analysis, safety data sheet, batch information, and shipping documents where applicable |
Many boronic acids require careful control of moisture, heat, and long-term storage conditions. A specific storage temperature should be taken from the current product documentation rather than generalized across all batches or packaging types. For example, some customers may request refrigerated storage at 2–8 °C, but this must be confirmed with the supplier for the exact material supplied.
Maison Chemical are exported all over the world and different industries with quality first. Our belief is to provide our customers with more and better high value-added products. Let's create a better future together.
Buyers may encounter this product in different packaging sizes, purity levels, or supply formats. Small quantities can support route scouting and analytical work, while larger quantities may be considered for process development after quality and logistics have been reviewed. Packaging may also differ according to the required protection from moisture, light, contamination, or mechanical damage.
It is important to distinguish this compound from related materials such as 4-fluorophenylboronic acid, 2-fluoro-4-methylphenylboronic acid, or other trifluoromethyl-substituted phenylboronic acids. These alternatives may share similar names but are not interchangeable without route-specific evaluation. We can help customers compare identity, purity, packaging, and availability before they commit to a purchase.
Start by matching the CAS number, structure, molecular formula, and intended reaction role. Ask for a recent batch-specific certificate of analysis and confirm whether the reported analytical method meets your internal requirements. If the material is intended for a regulated or quality-sensitive project, discuss documentation expectations before issuing a purchase order.
Quality review should include the stated purity, impurity profile, water content where relevant, and packaging controls. Supply review should cover the requested quantity, production status, available batch, estimated lead time, and whether repeat orders can be supported. A low initial price may not represent the best commercial option if documentation, consistency, or delivery planning is insufficient.
Before shipment, buyers should confirm the quotation currency, minimum order quantity, packaging unit, incoterm, destination restrictions, and required shipping documents. The compound should also be assessed under the buyer’s internal safety and regulatory procedures. We provide commercial information according to the requested quantity and destination because these factors can materially affect the final supply arrangement.
At Maison Chemical, we support customers sourcing 2-Fluoro-4-(trifluoroMethyl)phenylboronic Acid CAS 503309-11-3 for research, intermediate development, and commercial evaluation. Our role is to provide clear product identification, available specification information, packaging details, and a practical quotation based on the customer’s requirements. We avoid treating an unverified specification as a guaranteed result and encourage customers to review the batch documentation before use.
For a meaningful inquiry, please share the required quantity, target purity, destination country, preferred packaging, application stage, and documentation requirements. If you have a validated internal specification, sending it with the inquiry can reduce clarification time and help us assess the correct supply option. We can then confirm current availability, commercial terms, and the next documentation step.
2-Fluoro-4-(trifluoroMethyl)phenylboronic Acid CAS 503309-11-3 is a useful fluorinated aryl building block when your synthesis requires its specific substitution pattern and boronic acid reactivity. It is most appropriate for customers developing aromatic pharmaceutical intermediates, research compounds, or related fine chemical targets. The correct purchasing decision depends on confirmed identity, application-specific purity, documented handling requirements, and dependable supply planning.
The next step is to compare your internal specification with the supplier’s current batch documentation. Contact Maison Chemical with your required quantity, purity target, destination, and intended use, and we will help you assess availability, packaging, commercial terms, and supporting documents for your project.
The company is the world’s best 2-Fluoro-4-(trifluoroMethyl)phenylboronic Acid CAS 503309-11-3 supplier. We are your one-stop shop for all needs. Our staff are highly-specialized and will help you find the product you need.
Comments
Please Join Us to post.
0