If you are sourcing 1,4-Cyclohexanedione monoethylene acetal, CAS 4746-97-8, the most reliable approach is to qualify the material by identity, purity, analytical documentation, packaging, and supply capability—not by price alone. I identify this product as an organic intermediate used when a protected cyclohexanedione building block is required for further chemical synthesis. Its commonly referenced molecular formula is C8H12O3, with a molecular weight of approximately 156.18 g/mol.
At Maison Chemical, I help B2B buyers turn this general product name into a practical purchasing specification. The final decision should be based on your reaction route, required purity, scale, analytical method, delivery schedule, and regulatory documentation. Because commercial specifications can differ by manufacturer and grade, I recommend confirming every critical value against a current certificate of analysis before approval.
This guide is intended for pharmaceutical intermediate buyers, medicinal chemistry teams, process development groups, custom synthesis companies, and distributors evaluating CAS 4746-97-8. It is also useful for procurement professionals who need to compare several suppliers without relying on incomplete catalog descriptions. I focus on the information that affects qualification, production planning, and supply continuity.
The guide is especially relevant when a buyer is moving from laboratory-scale screening to repeated purchasing. At that stage, a product that appears equivalent on paper may still require closer review of assay method, impurity profile, lot consistency, packaging, and lead time. A documented qualification process reduces avoidable rework during scale-up.
1,4-Cyclohexanedione monoethylene acetal is a protected cyclic diketone derivative. In practical terms, one ketone functionality is converted into a cyclic ethylene ketal while the other carbonyl remains available for downstream transformation. This protection strategy can help chemists control reaction selectivity in multistep synthesis, although the suitability of the compound must be confirmed for the specific reaction conditions.
The CAS number 4746-97-8 should be used as the primary identity reference during supplier communication. Buyers should also verify the product name, molecular formula, molecular weight, structural representation, and analytical identity data because naming conventions may vary between catalogs. I recommend requesting an SDS and a lot-specific COA before placing a commercial order.
Suppliers may offer material intended for research, process development, or larger-scale manufacturing. These categories do not automatically represent a universal quality standard, so I advise buyers to define acceptance criteria directly. A research project may prioritize availability and small packaging, while a manufacturing program may require repeatable assay, controlled impurities, stable packaging, and a documented change-notification process.
The most important specification is usually assay or purity, supported by an appropriate analytical method such as HPLC, GC, NMR, or another agreed technique. Buyers should not compare purity percentages unless the testing method, calculation basis, and reporting format are understood. Depending on the process, water content, residual solvents, appearance, and identified impurities may also affect performance.
| Specification Area | What I Recommend Confirming | Why It Matters |
|---|---|---|
| Identity | CAS 4746-97-8, formula, molecular weight, and spectral or chromatographic confirmation | Confirms that the supplied material matches the requested intermediate |
| Assay and impurities | Method, acceptance limit, impurity reporting, and representative COA | Supports reaction consistency and process qualification |
| Physical description | Color, form, packaging condition, and storage recommendation | Helps receiving inspection and warehouse handling |
| Documentation | SDS, COA, batch number, manufacturing date, and country of origin where required | Supports internal approval, shipping, and compliance review |
For planning purposes, the molecular weight of approximately 156.18 g/mol is a useful data point for stoichiometric calculations. It should not, however, be treated as proof of purity or identity by itself. I also recommend confirming whether the supplier reports assay on an as-is basis or after correction for water, solvents, or other measurable components.
The main application question is whether the protected ketone structure fits your synthetic route. It may be considered for pharmaceutical intermediate synthesis, medicinal chemistry libraries, process research, and other applications requiring a functionalized cyclohexane building block. The correct choice depends on how the remaining ketone and acetal functionalities behave under your planned reaction conditions.
Before approving a supplier, I suggest testing a representative sample in the intended transformation. Important observations can include conversion, selectivity, work-up behavior, crystallization or isolation performance, and the impurity pattern after reaction. A catalog match is a starting point; process compatibility must be demonstrated by your own technical team.
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Start with the complete name, CAS number, molecular formula, and intended use. If your company uses an internal material code, include it in the inquiry to prevent confusion with related cyclohexanone, dioxolane, or protected carbonyl intermediates. I recommend specifying whether you need a standard commercial grade, a higher-purity grade, or a custom analytical package.
Define the minimum assay, impurity limits, appearance, water limit, residual solvent requirements, and packaging format before requesting quotations. For example, a buyer may require a minimum assay of 98.0% or 99.0%, but that number is meaningful only when the analytical method is stated. If the material will enter a regulated development program, your quality group should approve the specification and documentation list in advance.
Ask whether the supplier can support your expected order quantity, repeat orders, sample requests, and delivery destination. Confirm the standard package sizes and whether a smaller evaluation quantity is available before committing to a larger shipment. Lead time should be quoted in business days or calendar days, and the supplier should clarify whether it begins after purchase order, payment, or technical approval.
Price is only one part of total sourcing cost. Request the MOQ, packaging cost, freight basis, payment terms, production lead time, shelf-life information if available, and export documents required for your market. A quotation is easier to compare when all suppliers respond to the same specification and delivery assumptions.
Commercial pricing for CAS 4746-97-8 can vary according to purity, order quantity, packaging, production schedule, testing requirements, and shipping destination. I do not recommend using an unverified online price as a final benchmark because a low listed price may refer to a small research package or a different specification. The best comparison is a written quotation based on your required quantity and documentation.
MOQ should be discussed early, particularly when your project is still in route screening. A supplier that can provide an evaluation sample and then scale to larger packages may reduce qualification friction. For planning, buyers should request both sample lead time and production lead time, because these may be different and can affect project milestones by several weeks.
I also recommend checking how technical questions are handled before placing an order. A responsive supplier should be able to discuss specification interpretation, sample arrangements, documentation, packaging, and shipment planning without making unsupported performance claims. Clear communication at this stage is useful evidence of practical B2B support, although it does not replace your formal quality assessment.
Maison Chemical supplies 1,4-Cyclohexanedione monoethylene acetal CAS 4746-97-8 for international B2B evaluation and purchasing. I can help organize product identification, specification review, sample discussion, quotation preparation, packaging coordination, and export documentation according to the project requirements provided by the buyer.
For an efficient inquiry, please include the target quantity, desired purity, application stage, destination country, packaging preference, required documents, and expected delivery date. If you already have an internal specification or an approved supplier format, sharing it allows me to prepare a more relevant response. Final availability, price, lead time, and documentation should be confirmed for the specific order.
The best way to source 1,4-Cyclohexanedione monoethylene acetal CAS 4746-97-8 is to convert your project needs into a written, comparable specification. Confirm the chemical identity first, then review assay and impurities, application fit, documentation, packaging, MOQ, and delivery conditions. This framework helps distinguish a suitable long-term supply partner from a listing that provides insufficient technical information.
When you are ready to evaluate the material, contact Maison Chemical with your required quantity and specification. I can help you review the purchasing requirements, arrange the appropriate commercial discussion, and determine the next step for sample evaluation or B2B quotation.
The company is the world’s best 1,4-Cyclohexanedione monoethylene acetal CAS 4746-97-8 supplier. We are your one-stop shop for all needs. Our staff are highly-specialized and will help you find the product you need.
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