4-Hydroxyphenylboronic acid CAS 71597-85-8: Properties, Applications, and Sourcing Guide

Author: Doreen Gao

Oct. 13, 2026

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Tags: Chemicals

4-Hydroxyphenylboronic Acid CAS 71597-85-8: Properties, Applications, and Sourcing Guide

4-Hydroxyphenylboronic acid, also called 4-hydroxybenzeneboronic acid or p-hydroxyphenylboronic acid, is an aromatic boronic acid used as a building block in organic synthesis. Its key structural features are a boronic acid group and a phenolic hydroxyl group on a benzene ring, making it relevant to coupling chemistry and other synthesis planning. Its molecular formula is C6H7BO3, and its molar mass is approximately 137.93 g/mol. For procurement, confirm the required assay, analytical documentation, quantity, packaging, and delivery schedule against your intended application.

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Key Takeaways

  • CAS 71597-85-8 identifies 4-hydroxyphenylboronic acid; confirm the product name, CAS number, and formula on the supplier’s quotation and documentation.
  • The compound’s boronic acid group can support cross-coupling applications, while its phenolic hydroxyl group may affect reaction design and handling.
  • Suitability depends on application-specific requirements, including assay, impurity profile, packaging, and document needs.
  • Price, minimum order quantity, and lead time are supplier- and order-dependent; request a current quotation rather than relying on assumed market terms.

Who This Guide Is For

This guide is intended for procurement teams, process chemists, research and development groups, and distributors evaluating 4-hydroxyphenylboronic acid. It can help buyers prepare a more precise inquiry and compare supplier responses on relevant technical and commercial details. It is not a substitute for a project-specific safety review or confirmation of product specifications. Before committing material to a process, assess the supplier’s current documentation and your organization’s qualification requirements.

Basic Properties and Chemical Context

4-Hydroxyphenylboronic acid is an organoboron compound with a phenyl ring bearing a boronic acid substituent and a para-position hydroxyl group. The hydroxyl group is part of the molecule’s identity, not an optional additive. This combination makes it important to consider both functional groups when selecting reaction conditions, storage practices, and analytical checks. Appearance and other physical properties should be confirmed from the current product specification or batch documentation.

Identity and Specification Overview

Item Information to Confirm
Product name 4-Hydroxyphenylboronic acid; check for equivalent naming conventions on supplier documents
CAS number 71597-85-8
Molecular formula C6H7BO3
Molar mass Approximately 137.93 g/mol
Assay and impurities Confirm the stated method, acceptance criteria, and batch-specific result where available
Documentation Ask which specification, certificate of analysis, safety data, and shipping documents can be supplied

Do not treat a catalogue description as a substitute for the specification tied to the offered batch. Assay may be reported using different methods, and a stated purity does not by itself describe every impurity that could matter to a sensitive synthesis. If water content, residual solvents, metals, or a specific impurity are critical, state the requirement before ordering and ask whether it can be tested or documented. This helps align supplier capability with the actual project need.

Applications and Application Matching

A principal application area for arylboronic acids is carbon–carbon bond formation, including Suzuki–Miyaura coupling with suitable organic halides or related coupling partners. The phenolic group can be retained in a target structure or may need protection, depending on the substrate and reaction design. The appropriate choice is determined by the complete reaction scheme, not by the reagent name alone. Bench-scale evaluation and process-specific validation remain necessary.

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Common Project Contexts

  • Organic synthesis: Consider it as an intermediate or coupling building block when a hydroxy-substituted aryl fragment is required.
  • Medicinal and crop-protection research: It may be evaluated during synthesis of candidate molecules or intermediates; this does not imply approval or suitability for any particular end use.
  • Materials and specialty chemical research: Researchers may assess the compound where an aromatic hydroxyl group and boronic acid functionality are useful in a designed structure.
  • Route development: Teams should evaluate compatibility, conversion, work-up, and isolation alongside reagent cost and supply requirements.

How to Select a Suitable Grade

The best purchasing specification is the one that controls the quality attributes relevant to your process without requesting unsupported or unnecessary criteria. Start by defining the intended use, scale, and analytical controls. Then compare the supplier’s offered specification and documentation with those needs. Where a project has strict impurity limits, confirm feasibility before placing an order rather than assuming that a general assay statement covers them.

Buyer Selection Framework

  1. Confirm identity. Match the product name and CAS 71597-85-8 to the required molecular structure and internal material record.
  2. Set the quality requirement. Specify the required assay and any critical impurity, water, or residual-solvent limits. Ask how each reported result is measured.
  3. Define quantity and packaging. Request a quotation for the quantity needed now and indicate whether repeat supply may be required. For planning, buyers might ask for pricing at 25 g, 100 g, or 1 kg; these are example inquiry quantities, not a statement of stock or standard pack sizes.
  4. Review handling and shipping needs. Consult the supplier’s current safety and handling information, and communicate destination, packaging, and transport constraints.
  5. Assess continuity. If the material is part of a development or production route, ask about current availability, replenishment expectations, and change-notification practices where applicable.

Price, MOQ, and Lead Time

The price of 4-hydroxyphenylboronic acid can depend on requested quantity, specification, packaging, availability, and destination. Minimum order quantity and lead time are also quotation-specific, so buyers should obtain current written terms for their required grade and delivery location. A small evaluation order and a larger repeat order may have different unit economics and logistics. Compare quotations on the same basis, including assay, package size, shipping terms, documentation, and validity period.

To make an inquiry actionable, provide the CAS number, target quantity, required assay, intended application category, destination, and any special document or packaging requirements. If the project has a target delivery date, state it while requesting confirmation rather than assuming a standard lead time. A clear request reduces avoidable clarification and helps suppliers assess whether the offered material matches the project. Do not base a purchasing decision on price alone if the specification or batch documentation is incomplete.

Supplier Evaluation Checklist

Questions to Ask Before Ordering

  • Does the quotation identify the exact compound by name and CAS number?
  • Can the supplier provide the current specification and batch-specific quality documents available for the offered lot?
  • Are assay method, packaging, quantity, and quoted delivery terms clearly stated?
  • Can the supplier discuss additional analytical or impurity requirements before order confirmation?
  • Is the proposed supply arrangement appropriate for evaluation, repeat purchase, or planned scale-up?

Maison Chemical supports B2B inquiries for 4-hydroxyphenylboronic acid CAS 71597-85-8. Buyers can share their target quantity, specification, destination, and documentation needs so the team can respond with current availability and quotation details. Any batch-specific quality claims should be evaluated against the documentation supplied for that batch. For a new synthesis route, buyers should also confirm that the material meets their internal qualification and safety procedures.

Conclusion and Next Steps

4-Hydroxyphenylboronic acid CAS 71597-85-8 is a defined aromatic boronic acid building block with a molar mass of approximately 137.93 g/mol and potential utility in coupling chemistry and related synthesis work. Its suitability depends on reaction design and the buyer’s quality requirements, especially where the phenolic group or impurity profile matters. Confirm identity, assay, analytical documentation, quantity, packaging, price, and lead time before purchase. To request a quotation from Maison Chemical, provide your required quantity, target specification, destination, and any project-specific documentation needs.

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