3,5-Difluorophenol is a fluorinated aromatic phenol identified by CAS 2713-34-0. Its molecular formula is C6H4F2O and its molecular weight is approximately 130.09 g/mol. The molecule contains one phenolic hydroxyl group and two fluorine atoms positioned at the 3 and 5 locations of the benzene ring, making it a useful building block for organic synthesis and pharmaceutical intermediate development.
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In practical B2B purchasing, buyers should evaluate more than the chemical name. Identity confirmation, assay, impurity profile, packaging, safety documentation, batch consistency, and supply continuity all influence whether a material is suitable for laboratory, pilot-scale, or commercial use. At Maison Chemical, we support customer qualification by discussing the required specification, documentation package, quantity, and delivery expectations before quotation.
CAS 2713-34-0 refers specifically to 3,5-Difluorophenol. The “phenol” portion indicates an aromatic ring bearing a hydroxyl group, while “difluoro” indicates the presence of two fluorine substituents. The 3,5-substitution pattern is important because positional isomers can have different reactivity, physical behavior, and suitability for downstream synthesis.
The phenolic hydroxyl group can participate in chemical transformations commonly used in fine chemical synthesis. Depending on the reaction design, it may be converted, protected, or used to influence the electronic properties of the aromatic ring. The fluorine atoms can also modify molecular polarity, lipophilicity, metabolic behavior, and reaction selectivity in the final target molecule, although the actual effect must be assessed for each synthesis.
| Item | Information |
|---|---|
| Product name | 3,5-Difluorophenol |
| CAS number | 2713-34-0 |
| Molecular formula | C6H4F2O |
| Molecular weight | Approximately 130.09 g/mol |
| Functional groups | One phenolic hydroxyl group and two aryl fluorine substituents |
| Material category | Fluorinated aromatic building block and pharmaceutical intermediate |
Physical appearance, melting behavior, boiling behavior, and storage requirements should be confirmed from the current product specification and safety data sheet supplied for the relevant batch or grade. These details can vary in commercial documentation according to test method, purity, packaging configuration, and handling conditions. I recommend using the supplier’s current technical documents rather than relying only on an online catalog description.
A complete inquiry should normally define the required assay, identification method, water content, residual solvents, and any known or restricted impurities. For a regulated or advanced intermediate project, buyers may also request chromatographic data, batch-to-batch results, analytical methods, and a statement regarding trace metals or other process-related residues. The acceptance limits should be agreed before production or shipment because different applications may require different levels of control.
3,5-Difluorophenol may be used as a starting material or intermediate in the preparation of fluorinated aromatic compounds. In medicinal chemistry, fluorinated substituents are frequently explored during structure-activity relationship studies because they can alter the electronic and physical properties of candidate molecules. Its suitability depends on the target structure, the planned reaction sequence, and the required impurity controls.
Custom synthesis organizations may use this material when developing proprietary compounds, reference standards, or process routes. The phenolic group provides a useful handle for derivatization, while the fluorinated ring can remain part of the final molecular architecture. For these projects, reliable identity and consistent purity are often more important than simply obtaining the lowest initial price.
Universities, discovery laboratories, and specialty chemical manufacturers may purchase 3,5-Difluorophenol for route scouting and reaction development. Research quantities can support initial screening, while larger quantities may be required after a route is selected. Buyers should confirm whether the offered material is intended for research use, manufacturing use, or a specific regulatory application.
There is not always one universal specification for every use of 3,5-Difluorophenol. A discovery laboratory may accept a standard research grade, whereas a process-development or regulated project may require tighter impurity controls and a more detailed documentation package. I recommend defining the downstream reaction, target quantity, analytical requirements, and regulatory expectations before selecting a grade.
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Packaging should also match the intended use. Small containers may be practical for early laboratory work, while larger, appropriately sealed packages can reduce handling frequency during scale-up. The supplier should confirm the container material, closure system, labeling, lot traceability, and transport classification where applicable.
A capable supplier should be able to explain how product identity and purity are controlled. I suggest asking for a representative Certificate of Analysis, the analytical methods used, the available impurity information, and the current Safety Data Sheet. If the project is moving toward scale-up, ask whether the same or equivalent specification can be maintained across future batches.
Price should be evaluated together with minimum order quantity, lead time, production status, packaging, freight requirements, and documentation. A low unit price may not be commercially attractive if the minimum quantity is excessive or if the material requires additional testing after arrival. It is also useful to clarify whether the quoted lead time applies to available stock, production scheduling, or a custom specification.
For international purchasing, buyers should confirm export documents, invoice and packing-list requirements, transport restrictions, customs information, and the responsibilities of each party. These details are especially important for fluorinated phenolic materials because classification and handling requirements should be determined from the applicable SDS and shipping regulations. A written specification review before order placement can prevent avoidable delays.
3,5-Difluorophenol should be handled according to its current Safety Data Sheet and the procedures of the receiving organization. Phenolic compounds may present risks through skin, eye, inhalation, or ingestion exposure, but the exact hazard classification must be confirmed from the supplier’s current SDS rather than assumed from the product name alone. Appropriate engineering controls, protective equipment, labeling, and waste procedures should be established by the user’s qualified safety personnel.
During receipt, inspect the package for damage, verify the CAS number and lot information, and compare the supplied documentation with the purchase specification. Store the material under the conditions stated by the supplier, keeping the container properly closed and protected from incompatible conditions. Any change in color, container integrity, or documented storage history should be reviewed before use.
Maison Chemical supplies 3,5-Difluorophenol CAS 2713-34-0 for customers evaluating fluorinated aromatic intermediates and specialty chemical building blocks. We can discuss product identity, desired purity, quantity, packaging, documentation, and destination requirements as part of the quotation process. Our role is to help buyers align the commercial material with their actual synthesis and quality-control needs.
For a more efficient inquiry, please provide the requested quantity, target specification or assay, intended application, packaging preference, destination country, and required delivery window. If you need a specific impurity limit, analytical method, or document set, include it in the initial request so that the quotation can be reviewed against the correct requirements. Availability and lead time should be confirmed for each order because they depend on quantity, specification, and production planning.
3,5-Difluorophenol CAS 2713-34-0 is a defined fluorinated phenolic building block used primarily for chemical synthesis and intermediate development. It may be a suitable choice when your route requires the specific 3,5-difluorinated aromatic structure together with a reactive phenolic hydroxyl group. The final decision should be based on route compatibility, confirmed analytical data, safety requirements, and the specification needed for your application.
As the next step, prepare your target quantity, purity requirement, destination, and documentation needs, then request a batch-specific quotation and technical review. Maison Chemical can help assess the inquiry and provide available supplier information for 3,5-Difluorophenol. Contact our team with your requirements to begin a practical B2B sourcing discussion.
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